Based on the successful results of the Millennium Project (MEXT, 2000-2002) , HiPep Laboratories was founded by Dr. Nokihara focusing on development of novel biodetection systems, designated PepTenChip®, using designed peptide arrays, which can be mimicked by proteins. HiPep Laboratories also provide contract research in discovery and screening, syntheses, analyses & characterization of bio-molecules. Additionally HiPep produces laboratory equipments and consumers fundamentally developed in house use. The core technology, designated HiPep® Technology, is the life work of funder.
Wet laboratories were completed in Kyoto-city.
Memorial conference on HiPep-opening was held and current collaborators and dealers were attended. The company’s home page was completed; http://www.hipep.jp.
Okinawa bio-project was started and new additional laboratory was planned in the middle part of Okinawa-main Island.
Bio-Venture Project has been approved by the New Energy and Industrial Technology Development Organization and received a grant-in-aid.
HiPep-Okinawa Laboratory was opened and opening conference was held.
The prize in the Bio-Business Competition was bestowed.
Laboratory space in Kyoto has been expanded and laboratory for protein characterization was newly opened.
Celebration for five years anniversary and scientific conference was held with several invited speakers.
Both office and laboratory spaces in Kyoto head quarter were further expanded in it’s 1.4 times lager.
A five years national project, Research and Development Program for New Bio-industry Initiatives National Agriculture and Food Research Organization was started with grants.
The Program for Creating Okinawa Innovation was adopted by the Gant-in-Aid for Cabinet Office, Government of Japan and Okinawa Prefecture, and cell biology laboratories were completed in Kyoto and Okinawa.
Started trial marketing for the novel biochip, PepTenChip®.
The Adaptable and Seamless Technology Transfer Program through Target-Driven R & D, Japan Science and Technology Agency, was bestowed.
A novel application of PepTenChip® has been developed which can be used directly as a sample plate of MALDI-TOF mass spectrometry, thus the dual mode biodetection could be shown as a “hyphenated technologies”.
PepTenChip® sales was started. Immobilized peptide libraries were added on unique products lines.
Taking in account of economical influences cased by tsunami and earthquake in Tohoku, Okinawa lab is closed and all activities were focused in Kyoto.
The conference of 10 years anniversary-celebration of HiPep was performed and several invited speakers (scientific collaborators) gave their lectures.
All fundamental technologies concerning novel biodetection system, PepTenChip®, consisting of libraries for captured molecules, chip-plate (novel material made from amorphous carbon, high through-put arrayer and fluorescent detector) have been almost completed and starting the business.
Renewal of HiPep web-site (both Japanese and English)